What Is the COMT Gene? And How Does It Affect Your Health?
Nov 4, 2025 · Chronically stressed? Can't shake the blues? It could be your genes! In part 2 of this series, learn about how the COMT gene can affect health and well-being.
Do You Have COMT Gene Mutation, COMT Symptoms & Testing
Catechol-O-methyltransferase (COMT) or COMT enzyme activity is important to the areas of the pre-frontal cortex, this area of the brain is involved with personality, inhibition of behaviours, …
Catechol-O-methyltransferase - Wikipedia
Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine, and norepinephrine), …
What Is a COMT Mutation and How Does It Affect Your Health?
Jul 27, 2025 · The COMT enzyme is responsible for breaking down catecholamines, which include neurotransmitters like dopamine, norepinephrine, and epinephrine. This process, …
COMT gene: MedlinePlus Genetics
The COMT gene provides instructions for making an enzyme called catechol-O-methyltransferase. Learn about this gene and related health conditions.
How the COMT Gene Impacts Mental Health Treatment - Genomind
Feb 23, 2023 · The relative lack of dopamine transporters in the PFC means that dopamine levels in the PFC are largely determined by activity of the COMT enzyme. If clinically indicated, …
COMT Gene Mutation and its Impact on Health
Jan 17, 2025 · The COMT gene mutation plays a significant role in the body’s processing of neurotransmitters like dopamine, norepinephrine, and epinephrine. This gene encodes the …
Understanding the COMT Gene: Its Role and Effects - ClarityX Blog
Apr 3, 2024 · The COMT enzyme is involved in the methylation of catecholamines, including dopamine, norepinephrine, and epinephrine, by adding a methyl group to these …
COMT Gene Mutations: Symptoms, Test, and Treatment
Oct 29, 2024 · COMT mutations disrupt the breakdown of neurotransmitters, especially dopamine, resulting in mood swings, anxiety, and cognitive difficulties. You can test for COMT mutations …
COMT Gene: Neurotransmitter Levels, Estrogen Metabolism, and …
Jan 8, 2020 · The COMT gene controls the breakdown of neurotransmitters such as dopamine. Check your genetic raw data to see if you carry the COMT variants.