The autoimmunity associated with type 1 diabetes often begins in the first years of life, and the diagnosis of type 2 ...

Type 2 diabetes (T2D), the fastest growing non-infectious disease worldwide 1, is characterized by hyperglycemia caused by insufficient insulin release from pancreatic islets, often in combination ...

Loss of functional β-cell mass is the key mechanism leading to the two main forms of diabetes mellitus — type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). Understanding the ...

ZyVersa Therapeutics (ZVSA) highlights data from an article published in the peer-reviewed International Journal of Nanomedicine titled Small Intestinal Endocrine Cell Derived Exosomal ACE2 Protects ...

Type 2 diabetes (T2D) is marked by insulin resistance together with the progressive failure of pancreatic β-cells. Increasing ...

A joint effort involving research teams from Vanderbilt University Medical Center (VUMC) and the University of Michigan has linked the activities of a regulatory gene network and functional defects in ...

Type 2 diabetes (T2DM) is a systematic multi-organ metabolic disease, which is characterized by dynamic interplay among different organs. Pancreatic islet-liver axis is closely associated with normal ...

Diabetes mellitus (DM) is a metabolic disease characterized by pancreatic malfunction and poor production of insulin. Imagine your pancreas is a factory for insulin, a key hormone that keeps your ...

A comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to type 2 diabetes. The study, ...

Long-term Western diet impairs islet blood vessel function and insulin transport even after diet reversal and weight loss, according to a new study from researchers at Karolinska Institutet. A new ...

Researchers published the study covered in this summary on researchsquare.com as a preprint that has not yet been peer reviewed. Higher 25(OH)D levels associated with better homeostasis between ...

In a recent study published in Nature Communications, researchers used a murine model to demonstrate that functional excision of murine phosphatidylinositol transfer protein alpha (PITPNA) impaired ...