Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear. At this stage, known as gastrulation, ...
Toward the goal of generating high-quality embryo models in vitro, this study establishes a stepwise protocol to derive trophectoderm-like cells from mouse extended pluripotent stem (EPS) cells. These ...
Scientists in the Brivanlou lab used light-inducible gene expression (yellow circle) and embryo models to demonstrate that, at the start of gastrulation, body-axis formation requires an interplay ...
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A study published today in the journal Developmental Cell uncovers new insights into how the heart forms during the earliest stages of embryonic development.