The structure of DNA polymerase theta, which serves to fix double-strand breaks in DNA (at top) by bridging the hanging single-stranded ends and catalyzing DNA synthesis across the break. Researchers ...

Researchers at the University of Bristol have caught DNA-copying enzymes generating long stretches of genetic code without ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...

Like adding new letters to an existing language’s alphabet to expand its vocabulary, adding new synthetic nucleotides to the genetic alphabet could expand the possibilities of synthetic biology. This ...

Before this study, Pol-theta's structure had only been captured in an inactive state, leaving a major knowledge gap regarding how the enzyme interacts with DNA. It was like trying to determine how a ...

In July 2022, the World Health Organization (WHO) announced that monkeypox was a public health emergency of international concern. And, as of early December 2022, more than 82,000 human monkeypox ...

Since the dawn of science, one of mankind’s most impossible dreams has been the creation of life in a test tube. Last week scientists moved a step closer to making the dream possible. In Palo Alto, ...